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41.
液体中光击穿所激发声场的理论研究 总被引:1,自引:1,他引:0
以液体中光击穿所激发声场为研究对象,在等离子体椭球模型的基础上,为方便理论计算,简化等离子体椭球模型,提出了等离子体椭圆盘模型,对光击穿所激发声场进行了理论研究.得到了等离子体椭圆盘辐射声场的声压规律,并利用椭圆坐标变换,依据马修函数特性和模态的正交性,求得了等离子体椭圆盘振动位移的解析表达式. 相似文献
42.
ω-芋螺毒素属于海洋生物活性多肽,由24-31个氨基酸残基组成.特异性作用于电压敏感的钙离子通道(VGCCs),能够直接开发成药物或作为先导化合物进行新药开发.本文应用新型氨基酸残基结构描述符cscales和遗传偏最小二乘算法,对ω-芋螺毒素进行定量构效关系(QSAR)研究,并设计、构建了容量为2244个化合物的N-型和P/Q-型VGCC拮抗剂虚拟组合多肽库,然后分别采用QSAR模型预测和相似性搜索方法对组合多肽库进行了虚拟筛选.研究结果表明,建立的N-型和P/Q-型VGCC拮抗剂QSAR模型均具有较好的预测能力,交叉验证相关系数(CV-r2)均大于0.89.主成分分析和聚类分析结果表明,虚拟组合多肽库中化合物具有较好的结构多样性和差异性.通过虚拟筛选,得到了具有高预测活性的6个N-型和19个P/Q-型钙离子通道拮抗剂,为进一步的合成和活性评价奠定了理论基础.同时,本文建立的多肽QSAR预测模型和虚拟筛选策略,为其它多肽类化合物的定量构效关系研究和虚拟筛选提供了参考. 相似文献
43.
Sound absorption properties of natural kapok fibers have been investigated. Kapok fibrous assemblies with different bulk density, thickness, fiber length and orientation were manufactured, and their acoustical performances were evaluated by using an impedance tube instrument. Results show that the kapok fiber has excellent acoustical damping performance due to its natural hollow structure, and the sound absorption coefficients of kapok fibrous assemblies are significantly affected by the bulk density, thickness and arrangement of kapok fibers but less dependent on the fiber length. Compared with assemblies of commercial glass wool and degreasing cotton fibers, the kapok fiber assemblies with the same thickness but much smaller bulk density may have the similar sound absorption coefficients. Theoretical modelling of the acoustical damping performance of kapok fibers shows a good agreement with the experimental data. All the results demonstrate that kapok fiber is a promising light and environment-friendly sound absorption material. 相似文献
44.
XIONG Zi-jun DU Peng LI Bian XU Li-li ZHEN Xue-chu FU Wei .Key Laboratory of Smart Drug Delivery Ministry of Education & PLA 《高等学校化学研究》2011,(4):655-660
The serotonin 2A(5-HT2A) receptor has been implicated in several neurological conditions and potent 5-HT2A antagonists have therapeutic effects in the treatment of schizo phrenia and depression.In this study,a potent novel 5-HT2A inhibitor 05245768 with a Ki value of (593.89±34.10) nmol/L was discovered by integrating a set of computational approaches and experiments(protein structure prediction,pharmacophore-based virtual screening,automated molecular docking and pharmacological bioassay).The 5-HT2A recept... 相似文献
45.
S. BachaA. Bechiri F. BenmakhloufH. Allouache N. Bouarissa 《Physica B: Condensed Matter》2011,406(10):2021-2024
The investigation of optoelectronic properties of zinc-blende InPxSb1−x, semiconducting alloys by pseudopotential calculations is studied. The scheme uses the local empirical pseudopotential method, which involves the disorder effect into the virtual crystal approximation by introducing an effective potential disorder. Various quantities for the alloy of interest are calculated. The obtained results show a reasonable agreement with the available experimental data. Special attention has also been given to the compositional dependence of these studied quantities. 相似文献
46.
47.
为了提升某重型商用车前围的隔声性能,建立了用于分析前围传递损失的有限元-统计能量分析(FE-SEA)模型。针对前围结构复杂的特点,依据FE-SEA模型建模原则,提出了通过在表面创建声腔来确保能量在模型中的正确传递路径。将仿真结果与测试值对比,二者误差小于1.6 dB(A),验证了FE-SEA方法的准确性。用吸声材料与隔声材料复合设计前围声学包,采用正交试验法对前围声学包进行优化设计并对各个试验方案进行仿真计算。对仿真结果进行极差分析与方差分析,选出了在传递损失、重量和厚度三方面达到最佳平衡的声学包:毛毡(10 mm)+EPDM隔声垫(2 mm)。结果表明,优化后的前围传递损失在测试频率315 Hz~2000 Hz范围内最小提升了3.8 dB(A),最大提升了7 dB(A),前围的隔声性能得到较大的提升。 相似文献
48.
声学超材料及结构已被广泛研究,其超结构通常利用3D打印技术实现,当结构刚度较小或者面积较大时,由声固耦合所导致的声学效果与设计不符的情况广泛存在。本文针对含有膨胀腔类的超材料,研究了声固耦合对其声学性能的影响,采用有限元计算结合阻抗管实验的方法,得到其传递损失,分析了声固耦合现象对传递损失的影响。结果表明:薄壁膨胀腔结构的作用频率范围与只考虑声学理论计算的设计不符,声固耦合现象对传递损失产生显著影响;采用增加膨胀腔壁厚、减少膨胀腔内径或选择金属材料的方式,都可以使得声固耦合现象对传递损失的影响减小;仿真结果与实验结果基本吻合。该研究结果说明:对于膨胀腔类超材料,当刚度较小或者面积较大时,对其进行声固耦合分析是完全必要的。 相似文献
49.
In this paper, the effects of turbulence on sound generation and velocity fluctuations due to pressure waves in a large subsonic wind tunnel are studied. A trip strip located at different positions in the contraction part or at one position in the diffuser of a large wind tunnel is used to investigate the aforementioned phenomenon, and the results indicate that the trip strip has significant effects on sound reduction. The lowest turbulence intensity and sound are obtained from a trip strip with a diameter of 0.91 mm located either at X/L = 0.79 or at X/L = 0.115 in the wide portion of the contraction. Furthermore, the effect of monopole, dipole and quadrupole sources of aerodynamic noise at different velocities is investigated, and it is demonstrated that the contribution of the monopole is dominant, while the shares due to the dipole and quadrupole remain less important. In addition, it is found that the sound waves have a modest impact on the measured longitudinal turbulence and are generated essentially by eddies. 相似文献
50.
Analytical modeling of fluid loaded orthogonally rib-stiffened sandwich structures: Sound transmission 总被引:1,自引:0,他引:1
F.X. Xin 《Journal of the mechanics and physics of solids》2010,58(9):1374-1396
An analytic model is developed to investigate the wave propagation and sound transmission characteristics of an infinite sandwich structure reinforced by two sets of orthogonal rib-stiffeners when subjected to convective fluid-loaded pressure. The rib-stiffeners are assumed to be identical and uniformly spaced, which can exert not only tensional forces and bending moments but also torsional moments on the facesheets. Inertial terms of the tensional forces, bending moments and torsional moments are introduced to account for inertial effects arising from the mass of the rib-stiffeners. With the surrounding acoustic fluids restricted by the acoustic wave equation, fluid-structure coupling is considered by imposing velocity continuity condition at fluid-panel interfaces. By applying the Bloch theorem for periodic structures, the structural and acoustic responses are expressed in a superposition form of space harmonics for a given wavenumber. The application of the virtual work principle for one periodic element yields two infinite sets of simultaneous algebraic coupled equations, which are numerically solved by truncating them in a finite range insofar as the solution converges. The validity and feasibility of the analytic model is qualified by comparing model predictions with existing results, in which the necessity and advantage of the exact modeling of rib-stiffener motions are also demonstrated. Specifically, the influences of inertial effects arising from rib-stiffener mass, the periodicity spacing of rib-stiffeners, and the airborne as well as structure-borne paths on the transmission of sound across the sandwich structure are quantified and conclusions of significant practical implications are drawn. 相似文献